ALTERNATIVES FOR INNOVATIVE FORMULATIONS OF NATURAL SUNSCREENS: MORINGA OLEIFERA SEED EXTRACT WITH ETHANOL EXTRACTS OF PRÓPOLIS.

Abstract

Repeated or intense exposure to UV (ultraviolet) radiation causes skin changes by generating reactive oxygen species (ROS), which are harmful to tissues, causing burns, spots, erythema, photoaging and DNA mutations. The use of sunscreens is a means of preventing or reducing the effects of these exposures, as they have the ability to reflect and/or absorb them. Protectors can be of synthetic or natural origin. The development of actives capable of increasing the efficiency of sunscreens, especially those of plant origin, represents a growing demand in cosmetology. Moringa oleifera is a plant with varied pharmacological applications, it has a fast growth in tropical countries, and it is present in the Brazilian northeast and north of the state of Minas Gerais. Based on this, this study aims to evaluate the use of raw materials of natural origin as photoprotective agents, looking for trends in the consumer market. For this, novel formulations of dichloromethane extract of Moringa oleífera seeds, in association with different ethanolic extracts of propolis, were studied in relation to the photoprotective capacity. Regarding the propolis extracts (green, red and brown) 70% ethanolic were used. The photoprotective activity was studied in vitro. The results showed significant increases in FPS for the formulations. The high increase in sun protection was verified in green propolis, justified by the greater amount of flavonoids it presents. We concluded that the propolis extracts incorporated in the formulations with dichloromethane extract in the Moringa oleifera seeds showed a synergism in the intensification of the sun protection factor.