GENOTOXIC EFFECT OF TWO PAINTS USED IN TATTOO ART

Abstract

This study provides answers about the genotoxic effect of two inks used in tattoo art. There is currently no information about the genotoxic effects that some of the chemical compounds in paints can have on human health. The aim of this study was to know the genotoxic effects of black and white ink, mainly used in tattoo art. In this investigation, the micronucleus test was applied to peripheral blood cells from CD-1 mice and the structural chromosome aberration test to human lymphocyte cultures. The results obtained showed significant differences in the mean values ​​of dividing cells (%IM), in the frequency of micronuclei (%MCN) in the peripheral blood cells of mice and in the mean number of structural chromosomal aberrations of the cells. of human lymphocytes, for which they were subjected to Dunnett's multiple comparison test (p < 0.05). It was concluded that the chemical components of black and white inks have cytotoxic effects on peripheral blood cells of CD-1 mice and human lymphocyte cells. Regarding the genotoxic effects of these compounds, both dyes produce them in peripheral blood cells of CD-1 mice and only the white dye showed genotoxic effects on human lymphocyte cells at a concentration of 10 mg/mL.